SSRI/SNRI Therapy is Associated With a Higher Risk of Gastrointestinal Bleeding in LVAD Patients

Gastrointestinal bleeding (GIB) is common in left ventricular assist device (LVAD) patients. Serotonin release from platelets promotes platelet aggregation, and selective serotonin reuptake inhibitors (SSRI/SNRI) therapy inhibits the transporter responsible for re-uptake.

Source: Heart, Lung and Circulation - August 2, 2019 Category: Cardiology Authors: George Mawardi, Tim M. Markman, Rahatullah Muslem, Minoosh Sobhanian, Maureen Converse, Holly B. Meadows, Walter E. Uber, Stuart D. Russell, Rosanne Rouf, Bhavadharini Ramu, Daniel P. Judge, Ryan J. Tedford, Brian A. Houston Tags: Original Article Source Type: research