Upstream Region Of Carotid Plaque Shows More Intraplaque Hemorrhage In Stroke Patients: The Plaque At Risk (Parisk) Study

Background and Aims: Non-invasive visualization of intraplaque haemorrhage (IPH) as a key marker contributing to plaque vulnerability is rapidly gaining ground. However, the mechanisms contributing to IPH development are incompletely understood. We hypothesise that plaque deformations during every heartbeat lead to tissue damage (, thereby causing IPH. We aim to study non-invasively whether there is a difference in volume of IPH in the upstream region of the plaque in stroke patients with carotid stenosis and IPH.

Source: Atherosclerosis - August 2, 2019 Category: Cardiology Authors: G. Crombag, F. Schreuder HBM, F. Benali, D. van Dam-Nolen HK, C. Lucci, A. van der Steen F, M. Daemen JAP, W. Mess H, A. van der Lugt, P. Nederkoorn J, P. Hofman, R. van Oostenbrugge J, J. Wildberger E, M.E. Kooi Tags: E-poster session Source Type: research