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Medtronic’s Affinity Fusion Artificial Lungs for Bypass Surgeries

Medtronic received FDA clearance for its Affinity Fusion blood oxygenation/CO2 removal system for open heart surgeries. The new system was designed with particular engineering attention paid to reducing bubble formation and so preventing air embolisms.The Affinity Fusion was approved in Europe in September of last year and has already been used successfully in the U.S. at the Cleveland Clinic.Read More
Source: Medgadget Anesthesiology - Category: Anesthesiology Authors: Tags: Anesthesiology Cardiac Surgery Source Type: news

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CONCLUSION: Due to the increasing number of patients on long-term mechanical circulatory support, the chances are that physicians in the initial emergency admission are unfamiliar with these devices but need to operate them in emergency cases. Therefore, knowledge of these procedures and their complications becomes increasingly important. PMID: 29623383 [PubMed - as supplied by publisher]
Source: Der Anaesthesist - Category: Anesthesiology Authors: Tags: Anaesthesist Source Type: research
Many deceased by neurologic criteria donors are administered inhalational agents during organ recovery surgery —a process that is characterised by warm and cold ischaemia followed by warm reperfusion. In certain settings, volatile anaesthetics (VA) are known to precondition organs to protect them from subsequent ischaemia–reperfusion injury. As such, we hypothesised that exposure to VA during organ procu rement would improve post-graft survival. Lifebanc (organ procurement organisation [OPO] for NE Ohio) provided the investigators with a list of death by neurologic criteria organ donors cared for at three large...
Source: Anaesthesia and Intensive Care - Category: Anesthesiology Source Type: research
WITH OVER 4,000 lung transplant cases performed each year, lung transplantation remains a critical therapy for patients with a wide variety of end-stage lung diseases.1 Although long-term survival after lung transplantation is inferior compared with other solid organ transplants, such as heart, kidney, and liver, it does prolong life expectancy with a median survival of 7.4 years and 4.6 years for double- and single-lung transplant, respectively.1
Source: Journal of Cardiothoracic and Vascular Anesthesia - Category: Anesthesiology Authors: Tags: Editorial Source Type: research
By ANISH KOKA, MD No one knows who Bennie Solis is anymore. He had the misfortune of being born in the early 1960s marked for death. He had a rare peculiar condition called biliary atresia – a disease defined by the absence of a conduit for bile to travel from his liver to his intestinal tract. Bile acid produced in the liver normally travels to the intestines much like water from a spring travels via ever larger channels to eventually empty into the ocean. Bile produced in the liver with no where to go dams up in the liver and starts to destroy it. That the liver is a hardy organ was a fact known to the ancient Gree...
Source: The Health Care Blog - Category: Consumer Health News Authors: Tags: Uncategorized Source Type: blogs
“For those of us involved in heart and heart-lung transplantation, it was quite an experience to suddenly encounter an emptiness in the thorax, where moments before, a heart had been actively beating. Even a hardened person would find it difficult to control one’s inner emotions. Was this an act of meddling with the divine?”
Source: Journal of Cardiothoracic and Vascular Anesthesia - Category: Anesthesiology Authors: Tags: Editorial Source Type: research
CONCLUSIONS RVOTO is an unusual, but possible cause of severe arterial hypotension during general anesthesia induction. TEE is useful for the evaluation of severely hypotensive patients who do not respond to routine treatment with fluids and vasoconstrictors.
Source: International Journal of Surgery Case Reports - Category: Surgery Source Type: research
Publication date: Available online 9 August 2017 Source:Best Practice & Research Clinical Anaesthesiology Author(s): Vera von Dossow, Joseph Costa, Frank D'Ovidio, Nandor Marczin Transplantation is sadly a therapy to die for. The survival of the recipient with end stage heart or lung disease requires the demise of a human being via brain death or cessation of circulation with the most noblest final act of offering one’s organs to another. However, transplantation is constrained by severe hemodynamic, regulatory, inflammatory and metabolic stresses in the donor rendering the majority of offered organs unsuitable ...
Source: Best Practice and Research Clinical Anaesthesiology - Category: Anesthesiology Source Type: research
In this study, we focused on two pathways of cardiomyocytes or heart cells: the Hippo pathway, which is involved in stopping renewal of adult cardiomyocytes, and the dystrophin glycoprotein complex (DGC) pathway, essential for cardiomyocyte normal functions." Previous work had hinted that components of the DGC pathway may somehow interact with members of the Hippo pathway. The researchers genetically engineered mice to lack genes involved in one or both pathways, and then determined the ability of the heart to repair an injury. These studies showed for the first time that dystroglycan 1, a component of the DGC ...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
Lung transplantation is the treatment of last resort for many patients with end-stage lung disease. Although the first lung transplant operation was performed in 1962, it was not until the 1980s that lung transplantation became accepted more widely with the advent of better immunosuppression therapy. Since that time, many advancements have sequentially improved both the short-term and long-term outcomes of patients undergoing this therapy. Although lung transplantation traditionally was performed through a clamshell incision off-pump, the use of cardiopulmonary bypass (CPB) has expanded the indication to include patients w...
Source: Journal of Cardiothoracic and Vascular Anesthesia - Category: Anesthesiology Authors: Tags: Pro and Con Source Type: research
AbstractExtracorporeal membrane oxygenation (ECMO) or extracorporeal life support (ECLS) is a form of heart lung bypass that is used to support neonates, pediatrics, and adult patients with cardiorespiratory failure for days or weeks till organ recovery or transplantation. Venoarterial (VA) and venovenous (VV) ECLS are the most common modes of support. ECLS circuit components and monitoring have been evolving over the last 40  years. The technology is safer, simpler, and more durable with fewer complications. The use of neonatal respiratory ECLS use has been declining over the last two decades, while adult respiratory...
Source: Current Anesthesiology Reports - Category: Anesthesiology Source Type: research
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