Increased adhesive potential of antiphospholipid syndrome neutrophils mediated by beta ‐2 integrin Mac‐1

ConclusionAPS neutrophils demonstrate increased adhesive potential, which is dependent upon the activated form of Mac ‐1. In patients, this could lower the threshold for neutrophil‐endothelium interactions, NETosis, and possibly thrombotic events.This article is protected by copyright. All rights reserved.

Source: Arthritis and Rheumatology - July 27, 2019 Category: Rheumatology Authors: Gautam Sule, William J. Kelley, Kelsey Gockman, Srilakshmi Yalavarthi, Andrew P. Vreede, Alison L. Banka, Paula L. Bockenstedt, Omolola Eniola ‐Adefeso, Jason S. Knight Tags: Full Length Source Type: research