Detection of mutations in ampC promoter/attenuator gene in Escherichia coli from dairy cows in Rio de Janeiro and Mato Grosso, Brazil

Escherichia coli present the ampC naturally, and the observation of phenotypical resistance to cefoxitin is related to this gene deregulation. Mutations in the regulatory region in ampC cause exaggerated expression. The most frequent alterations in the E. coli AmpC promoter/attenuator leading to this overexpression is described at the positions: -88, -82, -42, -18, -1 and +58. Mastitis studi...
Source: African Journal of Microbiology Research - Category: Microbiology Source Type: research