Tumor-derived exosomes promote the in vitro osteotropism of melanoma cells by activating the SDF-1/CXCR4/CXCR7 axis

Bone metastases occur rarely in patients suffering from malignant melanoma, although their onset severely worsens both prognosis and quality of life. Extracellular vesicles (EVs) including exosomes (Exos) are ...

Source: Journal of Translational Medicine - July 19, 2019 Category: Research Authors: Francesco Mannavola, Marco Tucci, Claudia Felici, Anna Passarelli, Stella D ’Oronzo and Francesco Silvestris Tags: Research Source Type: research