The role of risedronate in osteopenia in Crohn's disease

We read with great interest van Bodegraven et al's1 paper about the treatment of osteopenia in patients with Crohn's disease. They have identified an evidence gap, as many studies of interventions to treat osteoporosis and prevent bone loss have been conducted on older and primarily female patients. In contrast, both male and female patients with Crohn's disease may develop osteopenia and osteoporosis at a younger age. The authors found that use of risedronate can improve bone density in the lumbar spine of patients with Crohn's disease. One of the exclusion criteria for patients in this study was vitamin D deficiency. Vitamin D deficiency has previously been noted to be common in patients with Crohn's disease.2 Vitamin D deficiency in patients with Crohn's disease has been known to correlate with bone loss for some time.3 Patients with Crohn's disease who are vitamin D...
Source: Gut - Category: Gastroenterology Authors: Tags: PostScript Source Type: research