Nesfatin-1 protects PC12 cells against high glucose-induced cytotoxicity via inhibiting oxidative Stress, autophagy and apoptosis.
CONCLUSION: These results support the idea that Nasfatin-1can protect PC12 cells against high glucose-induced cell injury by inhibition of apoptosis, autophagy and ROS production and can be considered as a potential drug for treatment of diabetic neuropathy.
PMID: 31323241 [PubMed - as supplied by publisher]
Source: Neurotoxicology - Category: Neurology Authors: Nazarnezhad S, Rahmati M, Shayannia A, Abbasi Z, Salehi M, Khaksari M Tags: Neurotoxicology Source Type: research