Diagnostic dose determination and efficacy of chlorfenapyr and clothianidin insecticides against Anopheles malaria vector populations of western Kenya

Malaria vector control is dependent on chemical insecticides applied to walls by indoor residual spraying or on long-lasting insecticidal nets. The emergence and spread of insecticide resistance in major malar...
Source: Malaria Journal - Category: Infectious Diseases Authors: Tags: Research Source Type: research

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Conclusions: Severe malaria is a highly frequent event in pregnant women, without differences by Plasmodium species. It shows early recognizable dangers signs. Hospital under-reporting was identified in 88% of severe cases as well as a lack of laboratory tests for a more comprehensive diagnosis. A protocol for the clinical diagnosis of pregnant women with malaria is required. PMID: 31529822 [PubMed - in process]
Source: Biomedica : Revista del Instituto Nacional de Salud - Category: International Medicine & Public Health Tags: Biomedica Source Type: research
Conclusiones. Los indicadores de competencia de la red local y de desempeño de los laboratorios intermedios alcanzaron altos estándares de calidad acordes con el proceso de entrenamiento implementado en el país. PMID: 31529838 [PubMed - in process]
Source: Biomedica : Revista del Instituto Nacional de Salud - Category: International Medicine & Public Health Tags: Biomedica Source Type: research
Conclusion: Uganda successfully developed a national multi-hazard emergency preparedness and response plan using the preparedness logic model. The plan is now ready for implementation by the Uganda MoH and partners. PMID: 31526179 [PubMed - in process]
Source: Global Health Action - Category: International Medicine & Public Health Tags: Glob Health Action Source Type: research
This study aims to investigate the antiatherogenic effects of the ethanol extract of U. diffracta and its mechanism.MethodA high fat diet and VD3 were used to establish the atherosclerotic rat model, with 0.004 g/kg/d of simvastatin as a positive control, fed with 0.7, 1.4, and 2.8 g/kg/d of Usnea ethanol extract for 21 days. The blood, liver, and aorta samples from each rat were collected after the last administration. Pharmacodynamic effects were evaluated. The inflammation related factors, the gene expressions of Toll-like receptor 5 (TLR5), myeloid differentiating factor 88 (MyD88), and nuclear factor-κB (NF-...
Source: Biomedicine and Pharmacotherapy - Category: Drugs & Pharmacology Source Type: research
Conclusions: Intensified social behavior change communication with active community participation is the need of the hour to prevent malaria and dengue occurrence and future outbreaks.
Source: Indian Journal of Public Health - Category: International Medicine & Public Health Authors: Source Type: research
Oregon Health&Science University just acquired 1,600 new research subjects. They’re small but mighty vectors for unpleasant itching at best and a deadly disease at worst. An insectary opened last week at the OHSU Vaccine&Gene Therapy Institute in Beaverton. It will house up to 200,000 mosquitoes to be used for malaria research. More than 200 million new cases of malaria are reported each year, mostly in Africa, with a child dying from the disease every two minutes. Currently vaccine candidates…
Source: bizjournals.com Health Care:Pharmaceuticals headlines - Category: Pharmaceuticals Authors: Source Type: news
Conclusion: Our findings indicated that both the crude leaf extracts and fractions of C. africana possess antimalarial effects, supporting the traditional claim of the plant. PMID: 31531119 [PubMed]
Source: Evidence-based Complementary and Alternative Medicine - Category: Complementary Medicine Tags: Evid Based Complement Alternat Med Source Type: research
Condition:   Malaria Interventions:   Drug: Presumptive treatment with Artemether-lumefantrine (AL);   Other: Enhanced vector control Sponsors:   University of California, San Francisco;   University of Namibia;   Ministry of Health and Social Services, Namibia;   University of Texas Southwestern Medical Center;   University of Notre Dame;   London School of Hygiene and Tropical Medicine Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
[Africa Check] Malaria kills "an average of 300,000 people yearly" in Nigeria, a health tech start-up tweeted in August 2019, prompting both interest and disbelief from users. The tweet attracted more than 2,300 reactions.
Source: AllAfrica News: Malaria - Category: Infectious Diseases Source Type: news
Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) is an important malaria virulence factor. The protein family can be divided into clinically relevant subfamilies. ICAM-1-binding group A PfEMP1 proteins also bind endothelial protein C receptor and have been associated with cerebral malaria in children. IgG to these PfEMP1 proteins is acquired later in life than that to group A PfEMP1 not binding ICAM-1. The kinetics of acquisition of IgG to group B and C PfEMP1 proteins binding ICAM-1 is unclear and was studied here. Gene sequences encoding group B and C PfEMP1 with DBLβ domains known to bind ICAM-1 were u...
Source: Infection and Immunity - Category: Infectious Diseases Authors: Tags: Cellular Microbiology: Pathogen-Host Cell Molecular Interactions Source Type: research
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