Synthesis of Recoded Bacterial Genomes toward Bespoke Biocatalysis.
Synthesis of Recoded Bacterial Genomes toward Bespoke Biocatalysis.
Trends Biotechnol. 2019 Jul 13;:
Authors: Nikel PI
Abstract
Ongoing efforts in synthetic biology aim at constructing (micro)organisms with (pre)defined properties. A recent breakthrough is the chemical synthesis of a recoded Escherichia coli genome by Fredens et al. (Nature, 2019). Besides the conceptual and technological tour de force, the consequences of this unprecedented effort for whole-cell biocatalysis are multifold.
PMID: 31311671 [PubMed - as supplied by publisher]
Source: Trends in Biotechnology - Category: Biotechnology Authors: Nikel PI Tags: Trends Biotechnol Source Type: research