Individual and diabetes presentation characteristics associated with partial remission status in children and adults evaluated up to 12 months following diagnosis of type 1 diabetes: an ADDRESS-2 (After Diagnosis Diabetes Research Support System-2) Study Analysis

Classically, people with type 1 diabetes mellitus T1D present with several weeks of osmotic symptoms (polyuria and polydipsia), fatigue and weight loss that, in the absence of treatment, progress rapidly towards diabetic ketoacidosis (DKA) [1]. This presentation is seen most frequently in children but symptoms and signs can be variable [2]. In adults, T1D may present even with appreciable residual insulin secreting capacity [3,4]. After diagnosis and initiation of insulin treatment, there may be a period of temporary restoration of β-cell function that can last from months to years [5,6].
Source: Diabetes Research and Clinical Practice - Category: Endocrinology Authors: Source Type: research