[Recommendations for vaccination against ROTAvirus in PREMature newborns (ROTAPREM)].

[Recommendations for vaccination against ROTAvirus in PREMature newborns (ROTAPREM)]. An Pediatr (Barc). 2019 Jul 06;: Authors: Álvarez Aldeán J, Ares Segura S, Díaz González C, Montesdeoca Melián A, García Sánchez R, Boix Alonso H, Moreno-Pérez D, en representación de la Sociedad Española de Neonatología (SENeo) y del Comité Asesor de Vacunas de la Asociación Española de Pediatría (CAV-AEP) Abstract Rotavirus (RV) is the leading cause of severe acute gastroenteritis in infants worldwide. Most children are infected by RV by the age of 5years, and especially in the first 2years. Two oral attenuated vaccines against RV are licensed in industrialised countries, which have proven to be safe and effective against the disease. The main objective of these vaccines has been to reproduce the natural history of infection and protect against severe disease in the first months of life. Preterm infants are at higher risk of severe RV infection compared to full-term infants and infants with normal birth weight. Data collected on RV vaccination in preterm infants demonstrated that RV vaccines are effective and safe, compared with full-term infants, with a marginal risk of horizontal viral transmission and dissemination when vaccination is performed during hospitalisation. Preterm infants frequently require admission to hospital after the beginning of the 12th week of life, which suggests that they should receive RV vaccines during ad...
Source: Anales de Pediatria - Category: Pediatrics Authors: Tags: An Pediatr (Barc) Source Type: research