Lacosamide: a study of exposures reported to US poison centers over a 9-year period - Teijido J, Kempf D, Laubach E, Zosel A, Borys D.

BACKGROUND: Lacosamide (Vimpat ®) is an anticonvulsant used to treat partial-onset seizures. Little is known about the characteristics and outcomes of patients exposed to lacosamide. OBJECTIVE: To characterize lacosamide exposures reported to US po...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

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BACKGROUND: The United States appears to be in the midst of an opioid epidemic. National data indicate a rise in emergency department visits for opioid-related causes over the past decade. This data, while important in helping to explain the magnitude of t...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news
BACKGROUND: Transdermal drug delivery systems (TDDS) pose special risks considering a large amount of drug they contain and their modified release properties. We sought to characterize TDDS exposures reported to the National Poison Data System (NPDS). ...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news
CONTEXT: This review discusses the range of clinical presentations seen with poisonings by the major toxic alcohols--methanol, ethylene glycol, and isopropyl alcohol. It outlines a straightforward diagnostic strategy and discusses in detail the current tre...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news
PURPOSE: The purpose of the study is to describe and compare the number and characteristics of opioid-involved fatal cases captured in the National Poison Data System (NPDS) and in US death certificates. METHODS: NPDS, which collects data on all ca...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news
Liver fibrosis is a wound-healing process induced by chronic liver injuries, such as nonalcoholic steatohepatitis, hepatitis, alcohol abuse, and metal poisoning. The accumulation of excessive extracellular matrix (ECM) in the liver is a key characteristic of liver fibrosis. Activated hepatic stellate cells (HSCs) are the major producers of ECM and therefore play irreplaceably important roles during the progression of liver fibrosis. Liver fibrogenesis is highly correlated with the activation of HSCs, which is regulated by numerous profibrotic cytokines.
Source: Translational Research - Category: Research Authors: Tags: Review Article Source Type: research
AIMS: To assess recommendations provided by the EXTRIP workgroup on extracorporeal toxin removal (ECTR) in lithium poisoning. METHODS: Retrospective assessment in a 128 lithium-poisoned patient cohort previously used to identify ECTR initiation cri...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news
Publication date: September 2019Source: Journal of Catalysis, Volume 377Author(s): Kuntao Huang, Hongquan Fu, Wen Shi, Hongjuan Wang, Yonghai Cao, Guangxing Yang, Feng Peng, Qiang Wang, Zhigang Liu, Bingsen Zhang, Hao YuAbstractMeNC catalysts have received intensive scientific interest as non-noble-metal single-atom catalysts (SAC) for electrochemical- and thermocatalytic reactions. However, the lack of understanding of its properties hinders further improvement of the catalytic performance. An interesting issue is the molecular details of the reaction involving more than one reactant, since the activation of the second re...
Source: Journal of Catalysis - Category: Chemistry Source Type: research
The technology can also be used to identify poisons as well as to monitor riversBeing palmed off with a young whisky when expecting an 18-year-old single malt can be a glass-half-empty moment. But now scientists have developed an “artificial tongue” that might make such skulduggery a thing of the past.The team, based in Scotland, say their device can be used to tell apart a host of single malts – a move they say might help in the fight against counterfeit products.Continue reading...
Source: Guardian Unlimited Science - Category: Science Authors: Tags: Alcohol Whisky Science UK news Source Type: news
BACKGROUND AND OBJECTIVES: Carbon monoxide is one of the most common causes of fatal intoxications in the United States, and multiple previous studies have demonstrated that cigarette smokers have higher levels of carbon monoxide in their blood. However, t...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news
Much has been made lately of millennials drinking less—and as America’s younger generations shift toward sobriety, recent research suggests the opposite is happening among its older ones. A new study published in the Journal of the American Geriatrics Society found that, from 2015-2017, more than 10% of adults 65 and older said they had binge drank—defined as consuming five or more drinks in one sitting for men, or four or more for women— in the past month, up from about 7% in 2006. That’s in keeping with other studies that have charted increases in excessive drinking among elderly adults, inc...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized embargoed study public health Source Type: news
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