Reply

We thank Dr Hansen for pointing out this rare phenomenon in infants, but would like to caution against drawing conclusions. Dr Hansen describes his own child with tracheomalacia whose clinical condition worsened with inhaled nitric oxide (iNO) and improved after withdrawal of the same. He postulates loss of tracheal tone with iNO. We have also observed “airway spasm,” though extremely rarely and only in infants with either Down syndrome or with severe bronchopulmonary dysplasia (BPD) and suspected tracheobronchomalacia.

Source: The Journal of Pediatrics - July 8, 2019 Category: Pediatrics Authors: Usha S. Krishnan, Sankaran S. Krishnan, Steven H. Abman Tags: LETTER TO THE EDITOR Source Type: research