Genome-wide association studies of atrial fibrillation: Finding meaning in the life of risk loci

Publication date: September 2019Source: IJC Heart &Vasculature, Volume 24Author(s): Henry Sutanto, Dobromir Dobrev, Jordi Heijman
Source: IJC Heart and Vasculature - Category: Cardiology Source Type: research

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Authors: Soo YO, Abrigo J, Chu W, Leung KT, Fong WC, Li SH, Li R, Ng PW, Wong KK, Wong LKS, Leung TWH PMID: 31416977 [PubMed - in process]
Source: Hong Kong Medical Journal - Category: General Medicine Tags: Hong Kong Med J Source Type: research
Authors: Duzen IV, Oguz E, Cekici Y, Yavuz F, Vuruskan E, Sincer I, Poyraz F, Alıcı H, Yuksek U, Demirtas AO, Sucu M Abstract New-generation oral anticoagulants (NOACs) are now preferred as a first-line treatment in the management of atrial fibrillation for prevention of thromboembolic complications. Mean platelet volume (MPV), one of the indicators of increased platelet activity, is also associated with an increased stroke risk in atrial fibrillation patients. The aim of this study was to evaluate changes in MPV, platelet distribution width (PDW) and plateletcrit following use of NOACs. The study included 1...
Source: Herz - Category: Cardiology Tags: Herz Source Type: research
Some non-invasive interventions (such as positive airway pressure ventilation) have the potential to improve outcome of invasive cardiac procedures. Remote ischemic preconditioning (RIPC) - induced by repetitive pre-interventional inflations of an arm-cuff to suprasystolic values - is one of them and effects on atrial fibrillation (AF) ablation are worth exploring. The RIPPAF (remote ischemic preconditioning for prevention of AF) study by Kosiuk et al. 1 is the first to measure electrophysiological effects of preconditioning in man with a view to potential antiarrhythmic effects.
Source: Heart Rhythm - Category: Cardiology Authors: Source Type: research
Authors: Guo S, Zhou L, Wang R, Lv Z, Xu H, Han B, Korantzopoulos P, Hu F, Liu T Abstract The present study reports on a family with two members affected by Danon disease but having different phenotypes. The clinical manifestations of Danon disease include cardiomyopathy, skeletal myopathy and different degrees of intellectual disability that varies greatly among patients. The present case study reports on two siblings, an older sister and a younger brother, with Danon disease from an affected pedigree, presenting with distinctly different phenotypes. The sister was diagnosed with dilated cardiomyopathy at the age ...
Source: Experimental and Therapeutic Medicine - Category: General Medicine Tags: Exp Ther Med Source Type: research
Condition:   Atrial Fibrillation Interventions:   Other: Weight Watchers;   Other: Slimming world;   Other: Leeds 'One You';   Other: NHS Choices;   Other: 5:2 diet;   Other: Individuals own personal plan Sponsor:   The Leeds Teaching Hospitals NHS Trust Not yet recruiting
Source: - Category: Research Source Type: clinical trials
We report a case of atrial fibrillation with rheumatic heart disease (RHD) who had intracardiac thrombus and cardiogenic cerebral embolism with rivaroxaban therapy. Intracardiac thrombus disappeared after switching from rivaroxaban to warfarin. Patients of RHD have the possibility of gradual progression of valvular disease even if they are old, so we need to distinguish nonvalvular atrial fibrillation from RHD before starting direct oral anticoagulants.
Source: Journal of Stroke and Cerebrovascular Diseases - Category: Neurology Authors: Tags: Case Report Source Type: research
Conclusions: Pulmonary malignant pathologies are more likely to develop POAF due to the need for lung resection and possibly mediastinal lymphadenectomy that stimulates the heart and pericardium and the vagus nerve. PMID: 31410090 [PubMed]
Source: Polish Journal of Cardio-Thoracic Surgery - Category: Cardiovascular & Thoracic Surgery Tags: Kardiochir Torakochirurgia Pol Source Type: research
Source: Clinical Nutrition - Category: Nutrition Authors: Tags: Nutrition and chronic disease/Nutritional assessment/Nutritional techniques and formulations Source Type: research
Authors: Guenancia C, Garnier F, Fichot M, Buffet P, Laurent G, Lorgis L Abstract In 2030, the European Union will include 14 to 17 million atrial fibrillation (AF) patients, with 120,000 to 215,000 new cases each year. The increase in the prevalence of this arrhythmia has led to the development of new therapeutic intervention strategies to manage the different aspects of this disease. Thus, endocavitary or epicardial ablation of AF, by radiofrequency or cryoablation, provides superior results to antiarrhythmic therapy in controlling symptoms and preventing heart failure in paroxysmal or persist...
Source: Revue de Medecine Interne - Category: Internal Medicine Tags: Rev Med Interne Source Type: research
Authors: Pype L, Embrechts L, Cornez B, Van Paesschen C, Sarkozy A, Miljoen H, Heuten H, Saenen J, Van Herck P, de Heyning CMV, Heidbuchel H, Claeys MJ Abstract Objective: The present study aims to identify the long-term effects of atrial fibrillation (AF) on atrial remodelling and on the progression of mitral/tricuspid valve regurgitation (MR/TR). Methods: The severity of MR/TR was assessed by the colour jet area and by multi-integrative approach at baseline and after a period of 65 ± 10 months in 37 patients with permanent AF, in 80 patients with non-permanent AF (of whom 43 were treat...
Source: Acta Cardiologica - Category: Cardiology Tags: Acta Cardiol Source Type: research
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