Sulforaphane protects against ethanol‐induced oxidative stress and apoptosis in neural crest cells by the induction of Nrf2‐mediated antioxidant response

Conclusions and implicationsThese results demonstrated that Nrf2‐mediated antioxidant response plays an important role in the susceptibility of NCCs to ethanol‐induced oxidative stress and apoptosis and that the protection of SFN against ethanol‐induced oxidative stress and apoptosis in NCCs is mediated by the induction of Nrf2 signaling.

Source: British Journal of Pharmacology - February 20, 2013 Category: Drugs & Pharmacology Authors: X Chen, J Liu, S‐Y Chen Tags: Research Paper Source Type: research