Bursting Enables GRP Neurons to Engage Spinal Itch Circuits

Publication date: 3 July 2019Source: Neuron, Volume 103, Issue 1Author(s): Hugues Petitjean, Philippe Seguéla, Reza Sharif-NaeiniIn this issue of Neuron, Pagani et al. (2019) find that itch signaling occurs only when GRP neurons fire action potentials in bursts. This enables GRP release and the activation of GRPR neurons, which help carry the itch signal to the brain.

Source: Neuron - July 5, 2019 Category: Neuroscience Source Type: research