Variability of von Willebrand factor-related parameters in endothelial colony forming cells.

CONCLUSIONS: We observed variations in morphology, maximum cell density, VWF production and angiogenic potential between healthy control ECFCs. These variations seem to be attributable to differences in aging and endoMT. Since variations correlate with cell density, we believe that ECFCs maintain a powerful tool to study vascular diseases. It is however important to compare cell lines with the same characteristics and perform experiments at maximum cell density. This article is protected by copyright. All rights reserved.
PMID: 31265169 [PubMed - as supplied by publisher]

Source: Thrombosis and Haemostasis - July 1, 2019 Category: Hematology Authors: de Jong A, Weijers E, Dirven R, de Boer S, Streur J, Eikenboom J Tags: J Thromb Haemost Source Type: research