Changing patterns of upper gastrointestinal bleeding over 23 years in Turkey.

CONCLUSION: Over the 23 years studied, the causes of NVUGB changed, probably because the population was increasingly elderly population and because of the use of anticoagulants and better therapeutic approaches to chronic duodenal ulcers. The use of emergency surgical hemostasis reduced, but mortality rate did not significantly change between the two specific periods. PMID: 31258140 [PubMed - as supplied by publisher]
Source: The Turkish Journal of Gastroenterology - Category: Gastroenterology Authors: Tags: Turk J Gastroenterol Source Type: research

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CONCLUSIONS: In patients requiring surgery during vvECMO therapy with perioperative transfusion of two or more PRBCs preoperative fibrinogen levels were significantly reduced compared to patients with transfusion of less than two PRBCs. No other analyzed lab value showed any predictive qualities in terms of bleeding. PMID: 31630509 [PubMed - as supplied by publisher]
Source: Minerva Anestesiologica - Category: Anesthesiology Tags: Minerva Anestesiol Source Type: research
This article compares the two devices to provide guidance on the selection and use of these monitoring systems. Their second-generation assays, TEG 6S and ROTEM Sigma, are also discussed. PMID: 31630507 [PubMed - as supplied by publisher]
Source: Minerva Anestesiologica - Category: Anesthesiology Tags: Minerva Anestesiol Source Type: research
Authors: special issue: “Focus on pediatric nephrology”, Chimenz R, Cannavò L, Viola V, Di Benedetto V, Scuderi MG, Pensabene L, Salvo V, D'Angelo G, Stroscio G, Impollonia D, Concolino D, Fede C, Alibrandi A, Cuppari C Abstract Urolithiasis is a well-known condition that can affect any part of the urinary tract. With a rate of 3-5% the incidence of upper urinary tract for long has been higher in adults (1-3), but recently it has increased among children reaching 3,3% . Indeed, more than 1% of all urinary stones are seen in patients aged less than 18 years (4). Pediatric urolithiasis is endemic i...
Source: Journal of Biological Regulators and Homeostatic Agents - Category: Biomedical Science Tags: J Biol Regul Homeost Agents Source Type: research
Delayed ischemic neurological deficit (DIND) is a major driver of adverse outcomes in patients with aneurysmal subarachnoid hemorrhage (aSAH), defining an unmet need for therapeutic development. Cell-free hemoglobin that is released from erythrocytes into the cerebrospinal fluid (CSF) is suggested to cause vasoconstriction and neuronal toxicity, and correlates with the occurrence of DIND. Cell-free hemoglobin in the CSF of patients with aSAH disrupted dilatory NO signaling ex vivo in cerebral arteries, which shifted vascular tone balance from dilation to constriction. We found that selective removal of hemoglobin from pati...
Source: Journal of Clinical Investigation - Category: Biomedical Science Authors: Source Type: research
A 63-year-old woman initially presented to a local urologist with a 9-month history of hematuria/vaginal bleeding followed by urinary retention. Computed tomographic imaging demonstrated a markedly distended urinary bladder with moderate bilateral hydronephrosis. Cystoscopy revealed no evidence of bladder tumor or urethral abnormality, and recurrent urinary tract infection was suspected. The patient developed worsened vaginal bleeding over a 6-month period, and anterior vaginal fullness was then appreciated on examination; she required a permanent indwelling catheter.
Source: International Journal of Radiation Oncology * Biology * Physics - Category: Radiology Authors: Tags: Gray Zone Source Type: research
This clear cell carcinoma may have arisen in the urethra or the anterior vagina.1 Primary urethral adenocarcinomas are very rare, but when they occur, the most common histology is clear cell carcinoma, probably of M üllerian origin and often associated with a urethral diverticulum. The symptom of prolonged vaginal bleeding, the physical examination placing the bulk of the tumor in the vagina, and the negative cystoscopy suggest that this tumor may have originated in the vagina.
Source: International Journal of Radiation Oncology * Biology * Physics - Category: Radiology Authors: Tags: Gray Zone Source Type: research
Conclusions: Female gender, increasing age, American Society of Anesthesiology classification, operative time, or a history of diabetes, chronic obstructive pulmonary disease, congestive heart failure, or a bleeding disorder are risk factors for prolonged hospitalization following total shoulder arthroplasty. Level of Evidence: Level III.
Source: Current Orthopaedic Practice - Category: Orthopaedics Tags: Original Research Source Type: research
ConclusionIn office hysteroscopic mechanical myomectomy with MyoSure® morcellator of submucosal fibromas was a highly effective therapy for women, at three years of follow-up. It appears to give satisfactory long-term results with a low recurrence rate and without significant complications.
Source: European Journal of Obstetrics and Gynecology and Reproductive Biology - Category: OBGYN Source Type: research
In conclusion, PUB is the main cause of UGIB, characterized by a significant rebleeding rate and mortality. PMID: 29590726 [PubMed - in process]
Source: Acta Clinica Croatica - Category: General Medicine Tags: Acta Clin Croat Source Type: research
An 87-year-old woman has a 6-year history of chronic kidney disease with medical control and valvular heart disease status post metal valve repair in 2011. She had underwent warfarin therapy for 5 years. Passage of melena developed 6 days prior to admission and normocytic anemia (hemoglobin: 4.0 mg/dl) was observed. Pale conjunctiva and epigastric tenderness were found during physical examination. Esophagog astroduodenoscopy revealed gastric ulcer (Forrest IIa), duodenal ulcer scars with luminal deformity and delayed gastric emptying. Although endoscopic hemostasis was underwent, passage of tarry stool presente...
Source: QJM - Category: Internal Medicine Source Type: research
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