EULAR recommendations for the use of imaging in large vessel vasculitis in clinical practice summary

AbstractLarge vessel vasculitis (LVV) is the most common form of primary vasculitis comprising of giant cell arteritis (GCA), Takayasu ’s arteritis (TAK) and idiopathic aortitis. Early diagnosis and treatment of LVV are paramount to reduce the risk of ischemic complications such as visual loss and strokes, vascular stenosis and occlusion, and aortic aneurysm formation. Use of imaging modalities [ultrasound (US), magnetic resonanc e imaging (MRI), computed tomography (CT) and [18F]-fluorodeoxyglucose positron emission tomography (PET)] has steadily increased to enable assessment of cranial and extracranial arteries, as well as the aorta. These imaging modalities are less invasive, more sensitive and readily available compared to temporal artery biopsy (TAB). Modern imaging methods have changed the role of TAB in diagnosing GCA and have replaced diagnostic angiography. Over the last two decades, several studies have evaluated the use of US, MRI, CT and PET in LVV. However, these various imaging tools are not yet uniforml y used in routine clinical practice and controversy exists as to which imaging modality best provides meaningful assessments of disease activity and damage in LVV. In January 2018, evidence-based recommendations for the use of imaging modalities in LVV were published. The aim of this review is to su mmarize the current evidence of imaging in patients with or suspected of having LVV, and to highlight the clinical implications of the EULAR recommendations.
Source: La Radiologia Medica - Category: Radiology Source Type: research

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Conclusion EMC should be considered first from an EE’s perspective, addressing concerns at the PCB level. MEs can get involved when enclosing the PCB or device. This is a collaborative effort. Both specialties should work through planning and execution. The ability to leverage a range of materials and components for EM enclosures allows engineers to make informed choices to meet the EMC requirements of a device. When considered at early stages, engineers can make EM an integral part of the design approach.
Source: MDDI - Category: Medical Devices Authors: Tags: Electronics Source Type: news
CASE SUMMARY: A 62-year-old previously healthy man presented with left lower quadrant pain and fever. Physical examination showed left lower quadrant peritonitis. Computed tomography scan showed a pelvic abscess with extraluminal air (Fig. 1). Intravenous antibiotics were started, and CT-guided percutaneous drainage was performed. The drain was removed 1 week after discharge. One week later, he presented with dysuria and pneumaturia and was started on antibiotics. Colonoscopy confirmed diverticulosis with no other mucosal abnormalities. He underwent a successful laparoscopic sigmoidectomy with colovesical fistula takedown.
Source: Diseases of the Colon and Rectum - Category: Gastroenterology Tags: Resident’s Corner Source Type: research
Conclusion The best algorithm to localise the culprit artery includes ST-elevation in leads II and V6 related to Cx, and ST-elevation in leads III, aVF and V3 related to right coronary artery. Our algorithm has been validated internally and externally, and works better than other previously published algorithms.
Source: Coronary Artery Disease - Category: Cardiology Tags: Myocardial Infarction/Cardiogenic Shock Source Type: research
Conclusions DCB angioplasty for de novo small coronary lesions in the real-world environment in Japan is effective with acceptable 12-month outcomes.
Source: Coronary Artery Disease - Category: Cardiology Tags: Myocardial Infarction/Cardiogenic Shock Source Type: research
Background Visual–functional mismatch between coronary angiography and fractional flow reserve (FFR) has been reported, and the underlying reason remains poorly understood. Therefore, the relationship between angiographic measurements and FFR was evaluated, and predictors for FFR in intermediate coronary artery stenosis were determined. Methods Consecutive 314 patients (405 lesions) with a lesion of 30–80% angiographic diameter stenosis who underwent invasive FFR were recruited. The myocardial area supplied by the coronary artery distal to the stenosis was evaluated using a modified version of the Bypass A...
Source: Coronary Artery Disease - Category: Cardiology Tags: Coronary Physiology Source Type: research
Background Cardiovascular disease is one of the leading causes of death worldwide. According to the results of various studies, protein convertase subtilisin kexin type-9 (PCSK9) was determined as a novel risk factor for stable coronary artery disease. Few studies have investigated the relationship between PCSK9 levels and the severity of coronary artery disease in patients with acute coronary syndrome; thus, we herein aimed to investigate this relationship in patients with non-ST-elevation myocardial infarction (NSTEMI) who underwent coronary angiography. Patients and methods Herein, 168 patients with NSTEMI were pro...
Source: Coronary Artery Disease - Category: Cardiology Tags: Risk Factors Source Type: research
Publication date: March 2020Source: Materials Today Communications, Volume 22Author(s): Alexandra L. Nikolaeva, Iosif V. Gofman, Alexander V. Yakimansky, Elena M. Ivan’kova, Natalia S. Gulii, Maria A. Teplonogova, Olga S. Ivanova, Alexander E. Baranchikov, Vladimir K. IvanovAbstractA series of polyimide/CeO2 nanocomposite films were fabricated based on three polymer matrices. The prepared films were characterized by scanning electron microscopy (SEM), thermomechanical analysis (TMA), and also simultaneous thermogravimetric (TGA) and differential thermal analysis (DTA), the latter two having been performed both in air...
Source: Materials Today Communications - Category: Materials Science Source Type: research
Publication date: April 2020Source: Materials Science and Engineering: C, Volume 109Author(s): Yun-shan Wei, Zhi-cheng Niu, Feng-qi Wang, Kun Feng, Min-hua Zong, Hong WuAbstractPickering emulsion (PE) stabilized by bio-compatible polymer nanoparticles (NPs) was first developed for the encapsulation of lipophilic tocopheryl acetate (TA) for its application in cosmetics. The poly(lactide-co-glycolide) (PLGA)/poly(styrene-co-4-styrene-sulfonate) (PSS) NPs were prepared by solvent displacement, and then they were used as emulsifier particles to fabricate TA-encapsulated PE. It was found that the TA encapsulation efficiency was...
Source: Materials Science and Engineering: C - Category: Materials Science Source Type: research
Publication date: 15 February 2020Source: Materials Letters, Volume 261Author(s): Farahnaz Haftlang, Abbas Zarei-Hanzaki, Hamid Reza AbediAbstractTi–29Nb–14Ta–4.5Zr (TNTZ) bio-alloy was processed against Ti–6Al–4V extra-low interstitial as a counter-body material in sliding friction mode under the low applied load of 2 N and very high sliding velocity of 300 mm/s. The near-surface micro-texture evolution induced by frictional force has been investigated in detail using Electron back-scattered diffraction analysis in scanning electron microscope (SEM-EBSD) and Angle selective back-sca...
Source: Materials Letters - Category: Materials Science Source Type: research
We describe a comprehensive effort that merges and harmonizes a large-scale dataset of 10,477 structural brain MRI scans from participants without a known neurological or psychiatric disorder from 18 different studies that represent geographic diversity. We use this dataset and multi-atlas-based image processing methods to obtain a hierarchical partition of the brain from larger anatomical regions to individual cortical and deep structures and derive age trends of brain structure through the lifespan (3–96 years old). Critically, we present and validate a methodology for harmonizing this pooled dataset in the presenc...
Source: NeuroImage - Category: Neuroscience Source Type: research
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