Incidence of total hip and total knee replacements from the prospective epidemiologic risk factor study: considerations for event driven clinical trial design

Osteoarthritis (OA) leads to joint failure and total joint replacement (TJR, either hip (H) or knee (K)). Worsening of pain and joint space narrowing are believed to be surrogates for joint failure; however, w...

Source: BMC Musculoskeletal Disorders - June 26, 2019 Category: Orthopaedics Authors: Cecilie L. Bager, Morten Karsdal, Asger Bihlet, Christian Thudium, Inger Byrjalsen and Anne C. Bay-Jensen Tags: Research article Source Type: research