Incidence of Silent Thrombosis in Patients Younger Than 60 Years With Myeloproliferative Neoplasms: Single-Center Egyptian Study

ConclusionWe recommend routine screening for venous thrombosis in any case of MPN when diagnosed and screening for MPNs in any patient with venous thrombosis especially of the portal vein or atypical sites. If MPN patients present with increasing pruritus or abdominal pain, they also should be screened for venous thrombosis. Further research on a large scale in MPN age groups younger than 60 years regarding pathogenesis of thrombosis is highly recommended.
Source: Clinical Lymphoma Myeloma and Leukemia - Category: Cancer & Oncology Source Type: research

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Publication date: Available online 16 October 2019Source: Colloids and Surfaces A: Physicochemical and Engineering AspectsAuthor(s): Fiammetta Nigro, Cristal Cerqueir, André Rossi, Verônica Cardoso, Alane Beatriz Vermelho, Eduardo Ricci-Júnior, Elisabete P. dos Santos, Claudia Regina E. MansurAbstractCoenzyme Q10 (CQ10) is a lipophilic substance synthesized endogenously by the body that has antioxidant, photoprotective and wound-healing properties. However, when applied exogenously in topical preparations, there are obstacles to its permeation through the stratum corneum due to its high molar mass, low ...
Source: Colloids and Surfaces A: Physicochemical and Engineering Aspects - Category: Chemistry Source Type: research
Conclusions: It appears that further studies are necessary to explain this problem, perhaps to include an evaluation of TF levels in psoriatic skin. PMID: 31616219 [PubMed]
Source: Advances in Dermatology and Allergology - Category: Dermatology Tags: Postepy Dermatol Alergol Source Type: research
Authors: KamiƄska-Winciorek G, Cybulska-Stopa B, Lugowska I, Ziobro M, Rutkowski P Abstract The introduction of immunotherapy into the treatment of cancer patients has revolutionised the oncological approach and significantly improved patient survival. The key drugs are immune checkpoint inhibitors (CPIs), whose mechanism of action is to elicit immune response against cancer cell antigens. Three types of CPIs are currently used and approved: an anti-CTLA-4 antibody, ipilimumab; anti-PD-1 antibodies, nivolumab and pembrolizumab; and anti-PD-L1 antibodies: atezolizumab, avelumab and durvalumab. CPIs have been widely...
Source: Advances in Dermatology and Allergology - Category: Dermatology Tags: Postepy Dermatol Alergol Source Type: research
CONCLUSION: Patients' qualitative feedback highlighted the potential feasibility and adaptability of the program for this population. The results of this preliminary study show promising avenues for research in the field of cancer patients' adaptive coping enhancement as well as reduce anxiety and depression symptoms. This type of workshop can be considered as complementary to individual psychotherapies as they may tap into different mechanisms that help foster psychological flexibility as the group format enhances decentering processes. Further research avenues are proposed in order to assess the efficacy of such interven...
Source: L Encephale - Category: Psychiatry Tags: Encephale Source Type: research
The opioid epidemic has taken its toll on Missouri. According to the Centers for Disease Control and Prevention, drug-related deaths rose in Missouri last year even as national deaths fell. One part of the problem? Legally prescribed pills. According to data from the U.S. Drug Enforcement Administration made available by The Washington Post, 1.6 billion prescription pain pills (oxycodone and hydrocodone) were supplied to Missouri pharmacies between 2006 and 2012, the most recent yea r that data…
Source: bizjournals.com Health Care:Biotechnology headlines - Category: Biotechnology Authors: Source Type: news
AdventHealth opened one freestanding ER in Oviedo this week and is in the progress of completing another one. The $3.36 billion Altamonte Springs-based health care system opened a 19,000-square foot, 24-bed facility at 8100 Red Bug Lake Road near the Oviedo Mall. The ER includes two kid-friendly patient rooms, imaging technology like X-ray, CT scan and ultrasound equipment, as well as a medical laboratory . “AdventHealth has provided Central Florida residents compassionate, whole-person care for…
Source: bizjournals.com Health Care:Biotechnology headlines - Category: Biotechnology Authors: Source Type: news
Publication date: Available online 17 October 2019Source: Urology Case ReportsAuthor(s): Walid Smeoui, Ahmed Samet, Talel Touaiti, Nouri Rebai, Abderrazek Bouzouita, Mourad HadjslimèneAbstractA 52-year-old man with a history of right nephrectomy for a nonfunctioning kidney, consults after 22 years for fever with right lower abdominal pain. Surgical exploration was thereafter performed and the right ureteral stump was removed en bloc. Pathological examination of the right ureterectomy specimen revealed a significant acute and chronic ureteritis due to stone without any signs of malignancy. Owing to the low incidence ...
Source: Urology Case Reports - Category: Urology & Nephrology Source Type: research
We report a case of a 61 year-old-male who presented a terminal hematuria. Ultrasounds revealed a mass at the dome and the right of urinary bladder. A transurethral resection of the bladder tumor was performed. A pathological examination revealed a pT1 hight grade carciono-sarcoma of the urinary bladder with cartilaginous differentiation. Cystoprostatectomy with Bricker diversion and lymph node dissection were performed. The pathological examination of the surgical specimen revealed no residual tumor lesion.
Source: Urology Case Reports - Category: Urology & Nephrology Source Type: research
The objective was to determine whether changes in parathyroid hormone (PTH) levels are associated with changes in symptoms within this patient population.Study DesignProspective cohort.Setting &Participants165 adults with hyperparathyroidism secondary to kidney failure diagnosed, a range of dialysis vintages, and receiving regular hemodialysis from a US single-provider organization.ExposureChange in PTH levels over 24 weeks.Outcomes19 putative symptoms of secondary hyperparathyroidism measured up to 4 times using a self-administered questionnaire that assessed severity on a 5-level ordinal scale.Analytical ApproachLong...
Source: American Journal of Kidney Diseases - Category: Urology & Nephrology Source Type: research
Conclusionwe recommend routine screening for venous thrombosis in any case of MPNs once diagnosed and screening for MPNs in any patient with venous thrombosis especially of the portal vein or atypical sites. If MPN patients presented with increasing pruritus or abdominal pain, they should be also screened for venous thrombosis. Further research on large scale in MPN group age below 60 years regarding pathogenesis of thrombosis is highly recommended.
Source: Clinical Lymphoma Myeloma and Leukemia - Category: Cancer & Oncology Source Type: research
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