Incidence of Silent Thrombosis in Patients Younger Than 60 Years With Myeloproliferative Neoplasms: Single-Center Egyptian Study

Venous thrombosis screening is not routinely performed in patients with myeloproliferative neoplasms unless the patient is symptomatic. It has been reported that the incidence of thrombosis in elderly patients is much higher than in young patients. The aim of this work was to screen 73 patients with janus kinase 2-positive myeloproliferative disorder (MPN) for venous thrombosis and study its correlation with JAK2 allele burden and with MPN 10 score. Fifty-three patients were younger than 60 years. Only 3 patient were symptomatic with abdominal pain during screening. There was no significant difference in MPN 10 score between patients with active or previous thrombosis. We recommend routine screening for venous thrombosis in any patient with MPNs, and screening for MPNs in any patient with venous thrombosis.

Source: Clinical Lymphoma, Myeloma and Leukemia - May 12, 2019 Category: Hematology Authors: Mervat M. Mattar, Sahar Nassef, Noha M. El Husseiny, Mohamed Roshdy El Masry, Marwa Salah, Mohamed Abdelkader Morad, Ahmed Abdul Gawad Tags: Original Study Source Type: research