Characterizing mechanical and medical imaging properties of polyvinyl chloride-based tissue-mimicking materials.

Characterizing mechanical and medical imaging properties of polyvinyl chloride-based tissue-mimicking materials.
J Appl Clin Med Phys. 2019 Jun 17;:
Authors: He Y, Qin S, Dyer BA, Zhang H, Zhao L, Chen T, Zheng F, Sun Y, Shi L, Rong Y, Qiu J
Abstract
Polyvinyl chloride (PVC) is a commonly used tissue-mimicking material (TMM) for phantom construction using 3D printing technology. PVC-based TMMs consist of a mixture of PVC powder and dioctyl terephthalate as a softener. In order to allow the clinical use of a PVC-based phantom use across CT and magnetic resonance imaging (MRI) imaging platforms, we evaluated the mechanical and physical imaging characteristics of ten PVC samples. The samples were made with different PVC-softener ratios to optimize phantom bioequivalence with physiologic human tissue. Phantom imaging characteristics, including computed tomography (CT) number, MRI relaxation time, and mechanical properties (e.g., Poisson's ratio and elastic modulus) were quantified. CT number varied over a range of approximately -10 to 110 HU. The relaxation times of the T1-weighted and T2-weighted images were 206.81 ± 17.50 and 20.22 ± 5.74 ms, respectively. Tensile testing was performed to evaluate mechanical properties on the three PVC samples that were closest to human tissue. The elastic moduli for these samples ranged 7.000-12.376 MPa, and Poisson's ratios were 0.604-0.644. After physical and imaging characterization of the...

Source: Journal of Applied Clinical Medical Physics - June 16, 2019 Category: Physics Authors: He Y, Qin S, Dyer BA, Zhang H, Zhao L, Chen T, Zheng F, Sun Y, Shi L, Rong Y, Qiu J Tags: J Appl Clin Med Phys Source Type: research