Net survival in recurrence-free colon cancer patients

ConclusionsCNS-RF is a relevant measure of prognosis in patients who have already achieved a period of remission. Providing an updated estimation of prognosis in the years following diagnosis may improve the survivors’ quality of life and access to credit or insurance.
Source: Cancer Epidemiology - Category: Cancer & Oncology Source Type: research

Related Links:

CONCLUSIONS Emergency endoscopic placement of an intestinal stent is safe and effective in the treatment of patients with acute intestinal obstruction caused by colorectal cancer. It is also a safe and simple procedure for patients receiving advanced palliative treatment, which greatly improves their quality of life and is easy for patients' families to accept. PMID: 31322139 [PubMed - in process]
Source: Medical Science Monitor - Category: Research Tags: Med Sci Monit Source Type: research
Conclusions: The CCAT2/miR-200b/vascular endothelial growth factor (VEGF) axis plays important regulating effect in OSA through the PI3K/Akt and AMPK pathways. PMID: 31322006 [PubMed - in process]
Source: Artificial Cells, Nanomedicine and Biotechnology - Category: Biotechnology Tags: Artif Cells Nanomed Biotechnol Source Type: research
Abstract Predictive biomarkers are revolutionizing decisions about colon cancer treatment. Knowing which biomarkers are altered provides valuable information about which treatment may be more effective. DNA mismatch repair and microsatellite instability testing may also identify families that could benefit from further genetic evaluation to determine if there is hereditary risk for colon cancer. Nurses need to be able to explain what these biomarkers mean and how they affect treatment decisions, as well as recommend genetic counseling and testing for hereditary risk when appropriate. PMID: 31322618 [PubMed - in process]
Source: Clinical Journal of Oncology Nursing - Category: Nursing Authors: Tags: Clin J Oncol Nurs Source Type: research
ConclusionsShort-term mortality rates were high in octogenarians operated for colorectal cancer. Short-term mortality rates differ across four North European countries, but decreased over time for both colon and rectal cancer patients in all countries.
Source: European Journal of Surgical Oncology (EJSO) - Category: Surgery Source Type: research
Authors: Strand LA, Martinsen JI, Borud EK Abstract INTRODUCTION: In 2012, Norwegian news media reported on cases of brain cancer among Norwegian peacekeeping troops who served in Kosovo, allegedly caused by exposure to depleted uranium fired during airstrikes before the peacekeepers arrived in 1999. A first study followed 6076 military men and women with peacekeeping service in Kosovo during 1999-2011 for cancers and deaths throughout 2011. The study did not support to the idea that peacekeeping service in Kosovo could lead to increased risk of brain cancer or other cancers. However, the average time of follow-up ...
Source: Military Medicine - Category: International Medicine & Public Health Tags: Mil Med Source Type: research
A germline MBD4 mutation was identified in a patient with colorectal oligopolyposis and early‑onset cancer: A case report. Oncol Rep. 2019 Jul 17;: Authors: Tanakaya K, Kumamoto K, Tada Y, Eguchi H, Ishibashi K, Idani H, Tachikawa T, Akagi K, Okazaki Y, Ishida H Abstract A 42‑year‑old woman presented with ~30 adenomatous polyps of the left sided‑colon with early rectosigmoid cancer. The patient had no previous medical history and no familial history of inherited colorectal disease. No germline gene mutations associated with colorectal adenomatous polyposis, including APC regulator of WNT s...
Source: Oncology Reports - Category: Cancer & Oncology Tags: Oncol Rep Source Type: research
Expression of circular RNA CDR1‑AS in colon cancer cells increases cell surface PD‑L1 protein levels. Oncol Rep. 2019 Jul 19;: Authors: Tanaka E, Miyakawa Y, Kishikawa T, Seimiya T, Iwata T, Funato K, Odawara N, Sekiba K, Yamagami M, Suzuki T, Ishibashi R, Otsuka M, Koike K Abstract The expression of CDR1‑AS, a representative circular RNA, is closely linked with poor prognosis in gastrointestinal cancers, such as colon, liver, and pancreatic cancers. Although it is well known that CDR1‑AS antagonizes microRNA‑7 function through its sequence similarities in the brain, its biological function a...
Source: Oncology Reports - Category: Cancer & Oncology Tags: Oncol Rep Source Type: research
Diagnostic and prognostic values of integrin α subfamily mRNA expression in colon adenocarcinoma. Oncol Rep. 2019 Jun 28;: Authors: Gong YZ, Ruan GT, Liao XW, Wang XK, Liao C, Wang S, Gao F Abstract The integrin α (ITGA) subfamily genes play a fundamental role in various cancers. However, the potential mechanism and application values of ITGA genes in colon adenocarcinoma (COAD) remain elusive. The present study investigated the significance of the expression of ITGA genes in COAD from the perspective of diagnosis and prognosis. A COAD RNA‑sequencing dataset was obtained from The Cancer G...
Source: Oncology Reports - Category: Cancer & Oncology Tags: Oncol Rep Source Type: research
Authors: Meng S, Jian Z, Yan X, Li J, Zhang R Abstract The term 'long non‑coding RNAs' (lncRNAs) refers to all non‑protein coding transcripts>200 nucleotides in length. Dysregulation of lncRNAs has been identified in colorectal cancer, which is one of the more serious types of cancer worldwide, third place in the mortality rates, and is associated with poor prognoses. Novel evidence suggests that lncRNAs serve an important role in regulating the development and progression of colorectal cancer. In the present study, it was demonstrated that SNHG6 expression was downregulated in colorectal cancer tissues by r...
Source: Molecular Medicine Reports - Category: Molecular Biology Tags: Mol Med Rep Source Type: research
Construction of chimeric antigen receptor‑modified T cells targeting EpCAM and assessment of their anti‑tumor effect on cancer cells. Mol Med Rep. 2019 Jul 03;: Authors: Zhou Y, Wen P, Li M, Li Y, Li XA Abstract Colon cancer is a common malignancy worldwide and there is an urgent requirement to develop effective treatment strategies. In recent years, tumor immunotherapy has become a new method of effectively treating tumors. Chimeric antigen receptor (CAR) T cell technology combines the precise targeting specificity of monoclonal antibodies with the strong toxicity and persistence of cytotoxic T ce...
Source: Molecular Medicine Reports - Category: Molecular Biology Tags: Mol Med Rep Source Type: research
More News: Cancer | Cancer & Oncology | Colon Cancer | Colorectal Cancer | Epidemiology | France Health | Insurance