Additive immunosuppressive effect of leflunomide and hydroxychloroquine supports rationale for combination therapy for Sj ögren's syndrome.

Conclusion: A combination of LEF and HCQ at clinically applicable concentrations additively inhibits immune activation, supporting a potential implementation of this drug combination in pSS treatment. PMID: 31192747 [PubMed - as supplied by publisher]
Source: Expert Review of Clinical Immunology - Category: Allergy & Immunology Tags: Expert Rev Clin Immunol Source Type: research