Attenuation of Palmitic Acid –Induced Lipotoxicity by Chlorogenic Acid through Activation of SIRT1 in Hepatocytes

ConclusionCollectively, these findings show that supplementation with CGA protects hepatocytes from FFA ‐induced lipotoxicity through activation of SIRT1, which reverses the oxidative stress and dysfunction of mitochondrial biogenesis directly.

https://onlinelibrary.wiley.com/doi/abs/10.1002/mnfr.201801432?af=R

Source: Molecular Nutrition and Food Research - June 12, 2019 Category: Food Science Authors: Lele Yang, Jinchao Wei, Feiya Sheng, Peng Li Tags: Research Article Source Type: research