Temporal inhibition of mouse mammary gland cancer metastasis by CORM-A1 and DETA/NO combination therapy

Conclusion: The therapy was shown to have antimetastatic action and resulted in normalization of endothelial metabolism, diminution of platelet activation and inhibition of EMT process. The effect was more prominent during early stages of tumor dissemination. Such treatment could be applied to inhibit metastasis during the first stages of this process.

Source: Theranostics - June 13, 2019 Category: Molecular Biology Authors: Kseniia Porshneva, Diana Papiernik, Mateusz Psurski, Agnieszka Ł upicka-S ł owik, Rafa ł Matkowski, Marcin Ekiert, Marcin Nowak, Joanna Jarosz, Joanna Banach, Magdalena Milczarek, Tomasz M. Goszczy ń ski, Marcin Sie ń czyk, Joanna Wietrzyk Tags: Research Paper Source Type: research