Association of alpha hemoglobin –stabilizing protein (AHSP) gene mutation and disease severity among HbE—beta thalassemia patients

This study documents that among the HbE beta thalassemia patients with varying severity, an exon mutation in AHSP is significantly prevalent only among the TDT group. Further understanding of the mechanism will shed light upon the impact of AHSP in modifying the disease severity in thalassemia.

Source: Annals of Hematology - June 12, 2019 Category: Hematology Source Type: research