A Comparative Study of Genetic Profiles of Key Oncogenesis-Related Genes between Primary Lesions and Matched Lymph Nodes Metastasis in Lung Cancer

Conclusion: Since the heterogeneity of genetic profiling exists between primary lesion and LN metastasis lesion, multi-region lesion mutation profiling is required to fully understand the progression of NSCLC, and develop an appropriate therapeutic guide. Mutations in genes involved in cell proliferation, invasion and migration may be the genetic mechanism of metastasis.
Source: Journal of Cancer - Category: Cancer & Oncology Authors: Tags: Research Paper Source Type: research