Pituitary Tumors in Pregnancy
This article discusses the diagnosis and treatment of patients with prolactinomas, acromegaly, Cushing disease, and other pituitary tumors during pregnancy.
Authors: Plagens-Rotman K, Przybylska R, Gerke K, Jaracz K, Serafinowska J, Sadowska-Przytocka A, Adamski Z, Czarnecka-Operacz M PMID: 31320864 [PubMed]
CONCLUSIONS: Lessons from the successful delivery of maternal tetanus immunization in Malawi may be informative for similar countries considering new vaccines for pregnant women or striving to optimize the delivery of those currently provided. PMID: 31319932 [PubMed - in process]
In conclusion, these findings indicated that Zeb1 may promote placental implantation by activating the Akt signaling pathway, thus providing a theoretical basis for investigating the causes of MAP. PMID: 31322233 [PubMed - as supplied by publisher]
When IVF patients get pregnant, they know how important measuring their blood HCG level is, to monitor the health of their pregnancy.However , they aren't sure how to interpret these levels.The reason it can be hard to make sense of them is because the normal range varies vary so widely; and because they rise so quickly as the pregnancy grows.Remember that HCG levels are very dependent on the gestational age of the pregnancy.Also, tracking HCG levels over time gives us far more valuable information as compared to just a single level !Read more at www.drmalpani.com/knowledge-center/articles/hcgYou can register at www....
CONCLUSIONS: Most stakeholders considered different approaches to partner HIV testing to be acceptable, but concerns were raised about each. A choice-based approach may allow women to select their preferred method of partner testing; however, implementation challenges need to be addressed. PMID: 31321884 [PubMed - in process]
When young women use abortion services, the adolescent men who avoid becoming teenaged fathers go on to have better educational and financial futures than peers who do become teen fathers, a U.S. study suggests.Reuters Health Information
We report an unusual plurihormonal tumor co-expressing Pit-1 and SF-1 along with hormones made by cells of both lineages. Its simultaneous occurrence adjacent to a corticotroph tumor raises questions regarding the pathogenesis of these tumors. We pr opose the possibility of a stem cell tumor with multiple lineage differentiation. We hypothesize that pregnancy might have played a permissive role in tumorigenesis.
CONCLUSION: the history we report, therefore, confirms previous experiences reporting a possible favourable outcome of pregnancy in patients affected by acromegaly and add further information about the behaviour of giant pituitary tumors in patients underwent pregnancy. PMID: 30088454 [PubMed - as supplied by publisher]
ConclusionMedical treatment can be safely done stopped in patients with prolactinoma and acromegaly when pregnancy is confirmed and reinstituted when necessary. Prospective studies may help to determine the effects of medical treatment during gestation on the mother and fetus.
Abstract OBJECTIVE: To examine the monitoring, management, and outcomes of pituitary tumors in pregnancy. METHODS: A national, prospective, observational, population-based case series study was conducted in all U.K. consultant-led obstetric units over 3 years using the U.K. Obstetric Surveillance System. To evaluate rates of adverse pregnancy outcomes, women with a macroprolactinoma (10 mm or greater) or nonfunctioning pituitary adenoma, diagnosed before or during pregnancy, were compared with two comparison groups: 1) a U.K. Obstetric Surveillance System cohort with singleton (n=2,205) or twin (n=27) pregnan...