Perfluorocarbon nanoparticle-mediated platelet inhibition promotes intratumoral infiltration of T cells and boosts immunotherapy [Medical Sciences]

Cancer immunotherapy can stimulate and enhance the ability of the immune system to recognize, arrest, and eliminate tumor cells. Immune checkpoint therapies (e.g., PD-1/PD-L1) have shown an unprecedented and durable clinical response rate in patients among various cancer types. However, a large fraction of patients still does not respond to...

Source: Proceedings of the National Academy of Sciences - June 10, 2019 Category: Science Authors: Zaigang Zhou, Baoli Zhang, Wenjing Zai, Lin Kang, Ahu Yuan, Yiqiao Hu, Jinhui Wu Tags: Biological Sciences Source Type: research