Quantitative proteomics of MDCK cells identify unrecognized roles of clathrin adaptor AP-1 in polarized distribution of surface proteins [Cell Biology]
The current model of polarized plasma membrane protein sorting in epithelial cells has been largely generated on the basis of experiments characterizing the polarized distribution of a relatively small number of overexpressed model proteins under various experimental conditions. Thus, the possibility exists that alternative roles of various types of sorting...
Source: Proceedings of the National Academy of Sciences - Category: Science Authors: Paulo S. Caceres, Diego Gravotta, Patrick J. Zager, Noah Dephoure, Enrique Rodriguez-Boulan Tags: PNAS Plus Source Type: research