Lack of an Association between a Polymorphism in the KRAS 3 ′ Untranslated Region (rs61764370) and Endometriosis in a Large European Case-Control Study

Conclusion: A germ-line single-nucleotide polymorphism in thelet-7 microRNA-binding site of theKRAS gene was not associated with sporadic endometriosis in an infertile Caucasian population in this large case-control study. However, it remains possible that this gene variant may be a marker of treatment resistance. Further studies on the role of this polymorphism in endometriosis are needed.Gynecol Obstet Invest
Source: Gynecologic and Obstetric Investigation - Category: OBGYN Source Type: research