Risk of Major Gastrointestinal Bleeding With New vs Conventional Oral Anticoagulants —a Systematic Review and Meta-analysis

There is controversy over whether use of non-vitamin K antagonist oral anticoagulants (NOACs) associates with increased risk of major gastrointestinal bleeding (GIB) compared with conventional therapies (such as vitamin K antagonists or anti-platelet agents). We performed a systematic review and meta-analysis of data from randomized controlled trials and high-quality real-world studies.

Source: Clinical Gastroenterology and Hepatology - June 9, 2019 Category: Gastroenterology Authors: Zhi-Chun Gu, An-Hua Wei, Chi Zhang, Xin-Hua Wang, Le Zhang, Long Shen, Zheng Li, Mang-Mang Pan, Xiao-Yan Liu, Jun Pu, Hou-Wen Lin Source Type: research