Nek2B activates the wnt pathway and promotes triple-negative breast cancer chemothezrapy-resistance by stabilizing β-catenin

The chemotherapy-resistance of triple-negative breast cancer (TNBC) remains a major challenge. The Nek2B kinase and β-catenin serve as crucial regulators of mitotic processes. The aim of this study was to test...

Source: Journal of Experimental and Clinical Cancer Research - June 7, 2019 Category: Cancer & Oncology Authors: Honghong Shen, Wenpeng Yan, Jinyang Yuan, Ziyue Wang and Chen Wang Tags: Research Source Type: research