Correlation between CSF biomarkers of Alzheimer's disease and global cognition in a psychogeriatric clinic cohort.
CONCLUSION: CSF biomarkers correlated best with cognitive performance in OD. t-Tau correlated weakly with cognition in controls and patients with MCI. In AD, only p-Tau levels correlated with cognitive performance. This pattern, which has been reported previously, seems to indicate that CSF biomarkers might not be reliable as indicators of disease severity.
PMID: 31166546 [PubMed - as supplied by publisher]
Source: Revista Brasileira de Psiquiatria - Category: Psychiatry Authors: Radanovic M, Oshiro CA, Freitas TQ, Talib LL, Forlenza OV Tags: Braz J Psychiatry Source Type: research