The role of interleukin 22 in multiple sclerosis and its association with c-Maf and AHR.

The role of interleukin 22 in multiple sclerosis and its association with c-Maf and AHR. Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub. 2019 Jun 04;: Authors: Zarobkiewicz MK, Kowalska W, Slawinski M, Rolinski J, Bojarska-Junak A Abstract The aim of this paper was to summarise knowledge of IL-22 involvement in multiple sclerosis (MS) and the possible link between IL-22 and two transcription factors - AHR and c-Maf. The conclusion is that despite numerous studies, the exact role of IL-22 in the pathogenesis of MS is still unknown. The expression and function of c-Maf in MS have not been studied. It seems that the functions of c-Maf and AHR are at least partly connected with IL-22, as both directly or indirectly influence the regulation of IL-22 expression. This possible connection has never been studied in MS. PMID: 31162488 [PubMed - as supplied by publisher]
Source: Biomedical Papers of the Medical Faculty of the Univ Palacky Olomouc Czech Repub - Category: Biomedical Science Tags: Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub Source Type: research