Tumor mutational signatures in sebaceous skin lesions from individuals with Lynch syndrome

ConclusionTumor mutational signatures 6 and 15 and somatic mutation burden were effective in differentiating Lynch ‐related from non‐Lynch sebaceous lesions.

Source: Molecular Genetics & Genomic Medicine - June 3, 2019 Category: Genetics & Stem Cells Authors: Peter Georgeson, Michael D. Walsh, Mark Clendenning, Simin Daneshvar, Bernard J. Pope, Khalid Mahmood, Jihoon E. Joo, Harindra Jayasekara, Mark A. Jenkins, Ingrid M. Winship, Daniel D. Buchanan Tags: ORIGINAL ARTICLE Source Type: research