Association of serum Tocilizumab trough concentrations with clinical disease activity index scores in adult rheumatoid arthritis patients.

CONCLUSION: In the first 24 weeks of treatment with SC TCZ injections, TCZ concentrations are associated with clinical improvement, while body weight and BMI are inversely associated with TCZ concentrations. Personalizing the dose of SC TCZ to body weight may improve outcomes of clinical disease activity in RA patients. PMID: 31154416 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/31154416?dopt=Abstract

Source: J Rheumatol - May 31, 2019 Category: Rheumatology Authors: Arad U, Elkayam O Tags: J Rheumatol Source Type: research