Mo1318 THERAPEUTIC INR INCREASES ENDOSCOPIC YIELD OF IDENTIFYING CULPRIT LESION IN LEFT VENTRICULAR ASSIST DEVICE RECIPIENTS PRESENTING WITH UPPER GI BLEEDING

Gastrointestinal bleeding (GIB) is a common and often challenging issue among continuous flow left ventricular assist device (LVAD) recipients. These patients are predisposed to GIB due to a combination of anticoagulation and antiplatelet effects, one of which is an acquired von Willebrand syndrome. Studies have shown that up to 65% of LVAD recipients experience GIB, most commonly due to arteriovenous malformation (AVM) in the upper GI tract. Anticoagulation with a goal International Normalized Ratio (INR) 1.5-2.5 is mandatory in patients with LVAD to prevent device thrombosis, but can predispose to GIB.

Source: Gastrointestinal Endoscopy - May 31, 2019 Category: Gastroenterology Authors: Prianka Singapura, Andy Y. Lee, Kristen Tecson, Hollie Sheffield, Allen Jacob, Megan Marcom, Srikant Patlolla, Parag Kale, Hemangi Kale Tags: Monday abstract Source Type: research