Dexmedetomidine Sedation in Magnetic Resonance–Guided Focused Ultrasound Thalamotomy: A Case Series of 3 Patients
We report the first use of dexmedetomidine for sedation in magnetic resonance–guided focused ultrasound thalamotomy in 3 patients: none of them experienced relevant hemodynamic changes or apnea.
AbstractPurpose of ReviewLesioning therapies have been some of the earliest, most effective surgical treatments in movement disorders. This review summarizes recent studies, emerging modalities, and trends in lesioning procedures for movement disorders.Recent FindingsMagnetic resonance –guided high-intensity focused ultrasound (MRgFUS) is the newest incisionless technology for lesioning procedures in movement disorders. It has recent FDA approval for thalamotomy in essential tremor and tremor-dominant Parkinson disease. There are current studies exploring subthalamotomy and pall idotomy in PD. Gamma knife is another ...
This article details the clinical features of each of these disorders, as well as those of additional tremor disorders.
CONCLUSION: We have observed, in this short series, a pseudo-dyssynergia by subjects suffering from IPD. LEVEL OF EVIDENCE: 3. PMID: 31302008 [PubMed - as supplied by publisher]
INSIGHTEC, an Israeli firm, and GE Healthcare have won FDA approval and the European CE mark for the Exablate Neuro with the SIGNA Premier MRI. The Exablate Neuro, made by INSIGHTEC, delivers focused ultrasound into the brain as a treatment o...
Cognitive impairment and dementia are common in PD; however, no stable marker of cognitive dysfunction is available. Transcranial sonography can evaluate global and focal brain atrophy and has been widely used in the differential diagnosis of parkinsonism.
Condition: Parkinson Disease Intervention: Device: ExAblate Neuro Thalamotomy Treatment Sponsor: InSightec Recruiting
While the blood-brain barrier (BBB) protects the brain from infections, it also makes it difficult to get drugs that treat neurological conditions to where they’re needed. Now, researchers at Columbia University have shown that their ultrasound...