Stereoisomer-Specific Induction of G2/M Phase Arrest and Apoptosis by 9-(E,Z)-Hydroxyoctadecadienoic Acid in Mouse Lymphoma Cells.

In conclusion, 9-(E,Z)-HODE specifically induced G2/M phase arrest and apoptosis, and the decrease of NEDD8 expression might be involved in this effect. PMID: 31155590 [PubMed - in process]

https://www.ncbi.nlm.nih.gov/pubmed/31155590?dopt=Abstract

Source: Biological and Pharmaceutical Bulletin - June 4, 2019 Category: Drugs & Pharmacology Authors: Kodaka A, Hayakawa Y, AlSayegh RJ, Yasuhara T, Tomoda H, Oku T, Dan S, Tsuiji M, Tsuji T Tags: Biol Pharm Bull Source Type: research