HIV incidence during breastfeeding and mother-to-child transmission in Cape Town, South Africa

Despite widespread concerns about HIV incidence in pregnant and postpartum women, there are few data from Africa on HIV acquisition in breastfeeding and subsequent mother-to-child transmission. We measured HIV incidence in a prospective cohort of 413 peripartum and breastfeeding women who tested HIV-negative during pregnancy. In 377 woman-years accrued postpartum (median duration of follow-up, 1 year), there were seven women infected after delivery (postpartum incidence, 1.86/100 person-years; 95% confidence interval 0.88–3.89) with transmission to 2/7 (28%) infants.
Source: AIDS - Category: Infectious Diseases Tags: Research Letters Source Type: research