Two new physalin derivatives from Physalis alkekengi L. var. franchetii (Mast.) Makino.

Two new physalin derivatives from Physalis alkekengi L. var. franchetii (Mast.) Makino. Nat Prod Res. 2019 May 29;:1-4 Authors: Sun JL, Jiang YJ, Cheng L Abstract Two new physalin derivatives named 7β-ethoxyl-isophysalin C (1) and 3β-ethoxyl-2,3-dihydro-4,7-didehydrophysalin B (2) were isolated from Physalis alkekengi L. var. franchetii (Mast.) Makino. Their structures were determined by extensive NMR-spectroscopic analysis and HRESIMS data. Compounds 1 and 2 were tested for their cytotoxicity against PC-3 cancer cell lines. Compound 1 showed apparent moderate with IC50 values of 8.26 μM, whereas compound 2 exhibited no cytotoxicity against PC-3 cancer cell lines. PMID: 31140313 [PubMed - as supplied by publisher]
Source: Natural Product Research - Category: Biochemistry Authors: Tags: Nat Prod Res Source Type: research