Effects of antidepressant treatments on health service utilization and medical costs among patients with depression: a nationwide population-based retrospective cohort study in Taiwan

This study aimed to assess the associations between the use of different types of antidepressants and health service utilization and costs among depressed patients. Data used in this study were retrieved from the Taiwan National Health Insurance Research Database. We identified 447 411 new antidepressant users during the study period (2011–2015) and they were individually followed for a 1-year period. Two-part generalized estimating equation models were conducted. Results demonstrated that there was a substantial decrease in outpatient service utilized by patients undertaking serotonin antagonists and reuptake inhibitors (β = −0.2074), serotonin–norepinephrine reuptake inhibitors (β = −0.0452), tricyclic antidepressants (β = −0.1308), or other antidepressants (β = −0.0637), compared with their counterparts in the selective serotonin reuptake inhibitors group (all P 
Source: International Clinical Psychopharmacology - Category: Psychiatry Tags: Original Articles Source Type: research