Impact of Growth Hormone Therapy on Adult Height in Patients with < b > < i > PTPN11 < /i > < /b > Mutations Related to Noonan Syndrome

Conclusions: This study supports the advantage of rhGH therapy on adult height inPTPN11+ patients. In comparison,PTPN11– patients showed a poor response to rhGH. However, this PTPN11– group was small, preventing an adequate comparison among different genotypes and no guarantee of response to therapy in genes besidesPTPN11.Horm Res Paediatr
Source: Hormone Research in Paediatrics - Category: Endocrinology Source Type: research