Sequential Interventional Management of Osseous Neoplasms via Embolization, Cryoablation, and Osteoplasty.

Sequential Interventional Management of Osseous Neoplasms via Embolization, Cryoablation, and Osteoplasty. J Oncol. 2019;2019:5247837 Authors: Sundararajan SH, Calamita S, Girgis P, Ngo G, Ranganathan S, Giglio M, Gendel V, Goyal S, Nosher J, Roychowdhury S Abstract The purpose of this study is to determine if sequential interventional therapy can become a mainstay option in providing palliation from fastidious osseous neoplasms in patients with pain refractory to oral analgesia and radiotherapy. This retrospective monocentric study was approved by our institutional review board. Between July 2012 and August 2014, we reviewed 15 patients (6 women, 9 men; age range of 36-81 years) who underwent embolization followed by cryoablation, with or without osteoplasty. Patient demographics and tumor characteristics, including primary histology and the location of metastasis, were included in our review. Pain intensity at baseline, after radiotherapy, and after sequential interventional therapy was reviewed using the hospital electronic medical record. The use of oral analgesia and procedural complications was also noted. Data was then assessed for normality and a two-tailed Student's t-test was performed on mean pain scores for difference phases of treatment. While radiotherapy offers pain relief with a mean pain score of 7.25 ±1.5 (p =<.0001), sequential interventional therapy results in better comfort as demonstrated by a mean pain scor...
Source: Journal of Oncology - Category: Cancer & Oncology Tags: J Oncol Source Type: research