L1-ORF1p and Ago2 are involved in a siRNA-mediated regulation for promoter activity of L1-5'UTR.

CONCLUSIONS: L1-5'UTR harbors both sense and antisense promoter activity and a dsRNA-mediated regulation is responsible for L1-5'UTR regulation. Agos proteins and L1-ORF1p were engaged in this process.
PMID: 31112282 [PubMed - as supplied by publisher]

Source: Folia Histochemica et Cytobiologica - May 22, 2019 Category: Cytology Tags: Folia Histochem Cytobiol Source Type: research