Quantification of Pediatric Burn Scar Stiffness Using Acoustic Radiation Force Impulse Ultrasound Elastography

The purpose of this study was to quantify the stiffness of hypertrophic scars using acoustic radiation force impulse ultrasound elastography. Sixteen pediatric patients with hypertrophic scars resulting from burn injuries participated in this study (mean age: 5.13, standard deviation: 3.20). Values for the elastic modulus (E) of scar and control sites were obtained. Scarred areas were found to be almost four times stiffer than control sites (scar Emean  = 39.29 kPa compared with control Emean = 10.19 kPa) (p = 0.0004).
Source: Ultrasound in Medicine and Biology - Category: Radiology Authors: Tags: Original Contribution Source Type: research

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CONCLUSION: MR-HIFU shows good mid-term result for extra-abdominal desmoids with complete response for small lesions and stabilization of larger lesions. MR-HIFU for desmoids can be performed under regional anesthesia/sedation as outpatients. PMID: 31068030 [PubMed - in process]
Source: International Journal of Hyperthermia - Category: Internal Medicine Tags: Int J Hyperthermia Source Type: research
High Altitude Medicine&Biology, Ahead of Print.
Source: High Altitude Medicine and Biology - Category: Sports Medicine Authors: Source Type: research
In this study, we report the age-associated differences between fetal MSC (fMSC) populations and MSCs isolated from elderly donors with respect to their transcriptomes. We successfully reprogrammed fMSCs (55 days post conception) and adult MSC (aMSC; 60-74 years) to iPSCs and, subsequently, generated the corresponding iMSCs. In addition, iMSCs were also derived from ESCs. The iMSCs were similar although not identical to primary MSCs. We unraveled a putative rejuvenation and aging gene expression signature. We show that iMSCs irrespective of donor age and cell type re-acquired a similar secretome to that of th...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
Joana F. Reis1,2,3*, Pedro Fatela3,4,5, Goncalo V. Mendonca2,4, Joao R. Vaz2,3,6, Maria J. Valamatos2,4,5, Jorge Infante7, Pedro Mil-Homens2,4,5 and Francisco B. Alves1,2 1Laboratory of Physiology and Biochemistry of Exercise, Faculdade de Motricidade Humana, Universidade de Lisboa, Lisbon, Portugal 2Ciper, Faculdade de Motricidade Humana, Universidade de Lisboa, Lisbon, Portugal 3Universidade Europeia, Lisbon, Portugal 4Neuromuscular Research Lab, Faculdade de Motricidade Humana, Universidade de Lisboa, Lisbon, Portugal 5Biomechanics and Functional Morphology Laboratory, Faculdade de Motrocidade Humana, Univers...
Source: Frontiers in Physiology - Category: Physiology Source Type: research
This study aims to investigate the efficiencies of seven methods in C. albicans biofilm EM extraction, namely vortexing plus ultrasonication (VU), formaldehyde plus vortexing and ultrasonication (Formaldehyde-VU), EDTA plus vortexing and ultrasonication (EDTA-VU), NaOH plus vortexing and ultrasonication (NaOH-VU), ethanol plus vortexing and ultrasonication (Ethanol-VU), ion exchange resin plus vortexing and ultrasonication (IER-VU)—including cation/anion-exchange resin plus vortexing and ultrasonication (CER/AER-VU)—under the static and dynamic states. Subsequently, the extracted metabolites are analyzed with t...
Source: Frontiers in Microbiology - Category: Microbiology Source Type: research
This study demonstrated that the incidence of ischemic heart disease and death were three times higher among men with low birth weight compared to men with high birth weight (5). Epidemiological investigations of adults born at the time of the Dutch famine between 1944 and 1945 revealed an association between maternal starvation and a low infant birth weight with a high incidence of hypertension and coronary heart disease in these adults (23). Furthermore, Painter et al. reported the incidence of early onset coronary heart disease among persons conceived during the Dutch famine (24). In that regard, Barker's findin...
Source: Frontiers in Endocrinology - Category: Endocrinology Source Type: research
To evaluate the accuracy of PoCUS in predicting return of spontaneous circulation (ROSC), survival to hospital admission (SHA), and survival to hospital discharge (SHD) in adult non-traumatic, non-shockable out-of-hospital or emergency department cardiac arrest.
Source: Resuscitation - Category: Emergency Medicine Authors: Tags: Review Source Type: research
Summary: Presented is the case of an obese, 72 year-old diabetic man with a dorsal foot de-gloving injury. Whilst the tendons of extensor hallucis longus, extensor digitorum longus to all digits, and extensor digitorum brevis to hallux and second toe were intact after surgical debridement, none had any covering paratenon. The joint between the medial cuneiform and first metatarsal was open. Reconstructive options were limited by his age and co-morbidities. A novel, completely synthetic dermal matrix (NovoSorb BTM) was applied, after which the patient was discharged home to attend for dressings and review of integration p...
Source: Plastic and Reconstructive Surgery Global Open - Category: Cosmetic Surgery Tags: Case Report Source Type: research
Conclusion: The combination of ultrasound-guided RFA with hydrodissection very effectively treats benign thyroid nodules while reducing damage to the surrounding tissues. This method is safe and effective for treating benign thyroid nodules.
Source: Journal of Cancer Research and Therapeutics - Category: Cancer & Oncology Authors: Source Type: research
The evolution of VR hardware and software What’s the best VR will do VR, AR, MR or spatial computing? The potential of interactive immersive reality Challenges and obstacles in adoption How will immersive reality transform everyday life? What was the last time you met sci-fi? The dark side of technology Imagine that a doctor sits down in Starbucks, places some glasses on his head, instantly invokes five screens and starts doing his diagnostic work. Robert Scoble, virtual reality expert, and tech evangelist believes that will be possible in the coming years – sooner than we might think. He told us why his wi...
Source: The Medical Futurist - Category: Information Technology Authors: Tags: Great Thinkers AR augmented reality future HoloLens Innovation MR Oculus technology virtual virtual reality VR XR Source Type: blogs
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